CHIROSIL
Crown-Ether Chiral Stationary Phases
ChiroSil® RCA(+) and SCA(-) are proven chiral stationary phases for the
separation of amino acids and compounds containing primary amines.
• Excellent durability due to covalent bonding
• Available in both enantiomeric forms [RCA(+) and SCA(-)], which allows
for the inversion of peak elution order
• Columns are stable to 5,000 psi (~345 bar)
• Fast delivery—all sizes, anywhere in the world
• Columns are available in 5 and 10 μm particle sizes and analytical and
preparative dimensions
Chemistry
Chirosil RCA(+) and SCA(-) have (+) or (-)-(18-Crown-6)-tetracarboxylic acid
as a chiral selector, which is bonded to the silica support. The ChiroSil®
CSP is manufactured for use in high-performance liquid chromatography
(HPLC).
CHIROSIL ME
ChiroSil ME columns are for amino acid chiral analysis and have increased
capacity factors. Chirosil ME RCA(+) and SCA(-) have (+) or (-)-(18-Crown-
6)-tetracarboxylic acid as a chiral selector, which is bonded to the silica
support. In general, capacity factors on Chirosil ME are greater than on
standard Chirosil, while the separation factors and resolution are greater
on standard Chirosil than on Chirosil ME. Select Chirosil ME for applications
where greater retention and capacity are needed.