PIRKLE-TYPE COLUMNS
Exclusive to Regis, we offer additional chiral phases with Pirkle-Type (or commonly
referred to as brush-type) chemistries. Pirkle chiral stationary phases generally
fall into three classes: π-electron acceptor/π-electron donors, the π-electron
acceptors and the π-electron donors. With Pirkle phases, chiral recognition
occurs at binding sites. Major binding sites are classified as π -basic or π -acidic
aromatic rings, acidic sites, basic sites, and steric interaction sites. Aromatic
rings are potential sites for π - π interactions. Acidic sites supply hydrogens
for potential intermolecular hydrogen bonds; the hydrogen is often an amido
proton (N-H) from an amide, carbamate, urea, or amine. Basic sites, such as
π-electrons, sulfinyl or phosphinyl oxygens, and hydroxy or ether oxygens, may
also be involved in hydrogen bond formation. Steric interactions may also occur
between large groups.
Advantages of the Pirkle-Type Chiral Stationary Phases
• Long lasting, robust columns
• Covalently bonded selector
• Compatible with strong solvents for cleaning
• Compatible with SFC and SMB applications
• High Capacity
*ULMO*
The ULMO CSP has a general ability to separate the enantiomers of many racemate classes and is particularly good at separating the enantiomers of aryl carbinols. Available in (R,R) and (S,S) forms to invert elution order.
查看詳細管柱規格列表>>