The Original Immobilized Phase
• Excellent method development column with applicability to a wide
• range of compound classes
• Alternate selectivity to polysaccharide chiral stationary phases
• Covalently bonded for long term performance and broad mobile phase
• compatibility
• Broad range of particle sizes and dimensions for analytical to preparative
•scale separations
• High loading capacity for excellent scalability in preparative applications
• Choice of enantiomeric phases allows inversion of peak elution order
• Recognized as USP L102
Chemistry
General purpose Pirkle-type chiral phase designed to achieve selectivity
through pi-pi interactions, dipole moment, hydrogen bonding
interactions, and additional selectivity based on structure. Fully
endcapped and bonded to high purity silica. Covalent bonding makes it
compatible with all commonly used mobile phases, including aqueous
systems. This column can be used in both normal phase and reversedphase
with minimal equilibration time when switching between the two
modes.
Key functional groups of the Whelk-O 1 selector involved in
chiral recognition
Available in 1.8 μm UHPLC columns
• Increase throughput and resolution—Great for rapid chiral screening
• 1.8μm fully porous particles for high efficiency separations in both
• UHPLC and UHPSFC
• Stable, long term performance for long column lifetimes at high flow
• rates and pressures
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